BMH-21

Catalog No.: A14335

RNA polymerase inhibitor

BMH-21

BMH-21 Chemical Structure

CAS NO. 896705-16-1

BMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription.

Availability: In stock

Package Price Qty
5 mg
$40.00
10 mg
$65.00
25 mg
$120.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription.
Targets
RNA polymerase I
In vitro DMSO 5 mg/mL heating (13.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL heating (5.54 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.59 mL 137.96 mL 275.92 mL
0.5 mM 5.52 mL 27.59 mL 55.18 mL
1 mM 2.76 mL 13.8 mL 27.59 mL
5 mM 0.55 mL 2.76 mL 5.52 mL

*The above data is based on the productmolecular weight 362.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14335
Actions Inhibitor
M. Wt 362.43
Formula C21H22N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 896705-16-1
Synonyms BMH21, BMH 21
SMILES CN(C)CCNC(=O)C1=CC=CN2C1=NC3=CC4=CC=CC=C4C=C3C2=O

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