BMS-341400 is a potent, orally active selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 0.3 nM. By inhibiting PDE5, BMS-341400 effectively prevents the breakdown of cyclic guanosine monophosphate (cGMP), facilitating nitric oxide (NO)-induced smooth muscle relaxation in the corpus cavernosum, which promotes erectile function. This compound is primarily utilized in the study of erectile dysfunction and related pathways in sexual health research.
BMS-341400 is a potent, orally active selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 0.3 nM. By inhibiting PDE5, BMS-341400 effectively prevents the breakdown of cyclic guanosine monophosphate (cGMP), facilitating nitric oxide (NO)-induced smooth muscle relaxation in the corpus cavernosum, which promotes erectile function. This compound is primarily utilized in the study of erectile dysfunction and related pathways in sexual health research.
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