BMS 345541 is a cell-permeable and highly selective IKB kinase (IKK) inhibitor that binds at allosteric site of the enzyme and blocks NF-kB-dependent transcription in mice.
BMS 345541 is a cell-permeable and highly selective IKB kinase (IKK) inhibitor that binds at allosteric site of the enzyme and blocks NF-kB-dependent transcription in mice.
Targets
Target
Value
Chemical Information
Catalog Num
A11318
Formula
C14H18ClN5
Molecular Weight
291.8
CAS Number
547757-23-3
SMILES
CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN.Cl
Synonyms
BMS345541, BMS-345541
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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