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BMS 345541 is a cell-permeable and highly selective IKB kinase (IKK) inhibitor that binds at allosteric site of the enzyme and blocks NF-kB-dependent transcription in mice.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.27 mL | 171.35 mL | 342.7 mL |
| 0.5 mM | 6.85 mL | 34.27 mL | 68.54 mL |
| 1 mM | 3.43 mL | 17.14 mL | 34.27 mL |
| 5 mM | 0.69 mL | 3.43 mL | 6.85 mL |
*The above data is based on the productmolecular weight 291.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11318 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 291.8 |
| Formula | C14H18ClN5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 547757-23-3 |
| Synonyms | BMS345541, BMS-345541 |
| SMILES | CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN.Cl |
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