Catalog No.: A12559

IKK2/IKK1 inhibitor


BMS-345541 Chemical Structure

CAS NO. 445430-58-0

BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM

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5 mg

Regular Price: $80.00

Special Price $64.00

10 mg

Regular Price: $140.00

Special Price $112.00

25 mg

Regular Price: $280.00

Special Price $224.00

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Biological Activity

BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM
IKK2 (Cell-free assay) IKK1 (Cell-free assay)
0.3 μM4 μM
In vitro DMSO 8 mg/mL (31.32 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.17 mL 195.83 mL 391.67 mL
0.5 mM 7.83 mL 39.17 mL 78.33 mL
1 mM 3.92 mL 19.58 mL 39.17 mL
5 mM 0.78 mL 3.92 mL 7.83 mL

*The above data is based on the productmolecular weight 255.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12559
Actions Inhibitor
CAS No. 445430-58-0
Formula C14H17N5
M. Wt 255.32
Purity >98%
Synonyms BMS345541, BMS 345541

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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