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BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM
Targets
| IKK2 (Cell-free assay) | IKK1 (Cell-free assay) | |||
| 0.3 μM | 4 μM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 39.17 mL | 195.83 mL | 391.67 mL |
| 0.5 mM | 7.83 mL | 39.17 mL | 78.33 mL |
| 1 mM | 3.92 mL | 19.58 mL | 39.17 mL |
| 5 mM | 0.78 mL | 3.92 mL | 7.83 mL |
*The above data is based on the productmolecular weight 255.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12559 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 255.32 |
| Formula | C14H17N5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 445430-58-0 |
| Synonyms | BMS345541, BMS 345541 |
| SMILES | CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN |
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