BMS 599626 (AC480)

Name: BMS 599626 (AC480)
Brand: Adooq Bioscience
SKU: A11209
Rating: 100 (268 reviews)

Catalog No.: A11209

EGFR Inhibitor

BMS 599626 (AC480) Chemical Structure

CAS NO. 873837-23-1

BMS 599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50=22, 32 and 190 nM, respectively) with potential antineoplastic activity.

Availability: In stock

Package	Price	Qty
5 mg	Regular Price: $80.00 Special Price $64.00
10 mg	Regular Price: $140.00 Special Price $112.00
50 mg	Regular Price: $400.00 Special Price $320.00
100 mg	Regular Price: $700.00 Special Price $560.00
10mM * 1mL in DMSO	Regular Price: $150.00 Special Price $120.00
Custom Size	Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Bulk Inquiry

Get Free Sample

Price Match

Add to Wishlist

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Biological Activity

BMS 599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50=22, 32 and 190 nM, respectively) with potential antineoplastic activity.

Solubility *

In vitro (25°C)	DMSO	104 mg/mL (196.02 mM)
	Water	Insoluble
	Ethanol	18 mg/mL (33.92 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.63 mL	88.17 mL	176.34 mL
0.5 mM	3.53 mL	17.63 mL	35.27 mL
1 mM	1.76 mL	8.82 mL	17.63 mL
5 mM	0.35 mL	1.76 mL	3.53 mL

*The above data is based on the productmolecular weight 567.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A11209
Actions	Inhibitor
CAS No.	873837-23-1
Formula	C27H27FN8O3.HCl
M. Wt	567.1
Purity	>98%
Synonyms	BMS-599626, BMS599626, AC-480
SMILES	CC1=C2C(=NC=NN2C=C1NC(=O)OC[[email protected]@H]3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F.Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.