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Biological Activity
BMS-599626 (AC480) is a selective and orally bioavailable HER1 and HER2 inhibitor, with IC50s of 20 and 30 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.85 mL | 94.24 mL | 188.48 mL |
| 0.5 mM | 3.77 mL | 18.85 mL | 37.7 mL |
| 1 mM | 1.88 mL | 9.42 mL | 18.85 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.77 mL |
*The above data is based on the productmolecular weight 530.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21664 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 714971-09-2 |
| Formula | C27H27FN8O3 |
| M. Wt | 530.55 |
| Purity | >98% |
| Synonyms | AC480, AC 480, AC 480, BMS599626, BMS 599626 |
| SMILES | O=C(NC1=CN2C(C(NC3=CC4=C(N(CC5=CC=CC(F)=C5)N=C4)C=C3)=NC=N2)=C1C)OC[[email protected]]6NCCOC6 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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