Boc-10-Aminodecanoic acid is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs) and other conjugation applications. This compound features an alkane chain with a terminal carboxylic acid and Boc-protected amino groups, facilitating efficient formation of stable amide bonds when reacted with primary amines in the presence of coupling agents such as EDC or HATU. The Boc group can be deprotected under mild acidic conditions to yield the free amine, enabling further functionalization and applications in targeted protein degradation research.
Boc-10-Aminodecanoic acid is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs) and other conjugation applications. This compound features an alkane chain with a terminal carboxylic acid and Boc-protected amino groups, facilitating efficient formation of stable amide bonds when reacted with primary amines in the presence of coupling agents such as EDC or HATU. The Boc group can be deprotected under mild acidic conditions to yield the free amine, enabling further functionalization and applications in targeted protein degradation research.
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