Boc-2-(piperazin-1-yl)acetic acid dihydrate

Catalog No.: A84240
PROTAC Linker
Boc-2-(piperazin-1-yl)acetic acid dihydrate is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in enabling the selective degradation of target proteins through the recruitment of E3 ligases. Its application in chemical biology research supports the development of novel therapeutics aimed at various diseases by harnessing targeted protein degradation strategies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBoc-2-(piperazin-1-yl)acetic acid dihydrate is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in enabling the selective degradation of target proteins through the recruitment of E3 ligases. Its application in chemical biology research supports the development of novel therapeutics aimed at various diseases by harnessing targeted protein degradation strategies.
Product Information
Catalog NumA84240
FormulaC11H24N2O6
Molecular Weight280.32
CAS Number1049785-94-5
SMILESO=C(N1CCN(CC1)CC(O)=O)OC(C)(C)C.O.O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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