Boc-aminoxy-PEG4-acid

Catalog No.: A81985
PROTAC Linker
Boc-aminoxy-PEG4-acid is a polyethylene glycol (PEG) derivative designed as a linker for PROTAC (Proteolysis Targeting Chimera) systems. It facilitates the conjugation of E3 ligase ligands and target proteins, thereby enhancing the efficiency of targeted protein degradation. This versatile linker is crucial for researchers developing PROTAC-based therapeutics and studying the principles of targeted protein modulation. Its PEG structure contributes to increased solubility and improved pharmacokinetic properties in biological applications.
Grouped product items
Size Price Stock Qty
2mg
$45.00
In stock
5mg
$50.00
In stock
10mg
$55.00
In stock
25mg
$60.00
In stock
50mg
$65.00
In stock
100mg
$100.00
In stock
250mg
$235.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBoc-aminoxy-PEG4-acid is a polyethylene glycol (PEG) derivative designed as a linker for PROTAC (Proteolysis Targeting Chimera) systems. It facilitates the conjugation of E3 ligase ligands and target proteins, thereby enhancing the efficiency of targeted protein degradation. This versatile linker is crucial for researchers developing PROTAC-based therapeutics and studying the principles of targeted protein modulation. Its PEG structure contributes to increased solubility and improved pharmacokinetic properties in biological applications.
Product Information
Catalog NumA81985
FormulaC16H31NO9
Molecular Weight381.42
CAS Number2062663-68-5
SMILESO=C(OC(C)(C)C)NOCCOCCOCCOCCOCCC(O)=O
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