Boc-NH-PEG11-CH2CH2N3 is a PEG-based linker designed for use in the synthesis of PROTACs through targeted protein degradation. This compound features an azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. Its unique properties make it suitable for applications in chemical biology and drug discovery.
Boc-NH-PEG11-CH2CH2N3 is a PEG-based linker designed for use in the synthesis of PROTACs through targeted protein degradation. This compound features an azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. Its unique properties make it suitable for applications in chemical biology and drug discovery.
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