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$0.00 Biological Activity
Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.76 mL | 83.8 mL | 167.59 mL |
| 0.5 mM | 3.35 mL | 16.76 mL | 33.52 mL |
| 1 mM | 1.68 mL | 8.38 mL | 16.76 mL |
| 5 mM | 0.34 mL | 1.68 mL | 3.35 mL |
*The above data is based on the productmolecular weight 596.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13364 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 596.68 |
| Formula | C36H32N6O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1800070-77-2 |
| SMILES | C=CC(NC1=CC=C(N2)C(N(C3CCN(CC4=CC=C(C5=NC6=C(C(NC=C6)=O)C=C5C7=CC=CC=C7)C=C4)CC3)C2=O)=C1)=O |
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