Borussertib

Name: Borussertib
SKU: A13364
Price: 270 USD
Rating: 5 (288 reviews)

Catalog No.: A13364

Akt inhibitor

Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt.

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Data Sheet

SDS

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Biological Activity

Discription	Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt.

Chemical Information

Catalog Num	A13364
Formula	C36H32N6O3
Molecular Weight	596.68
CAS Number	1800070-77-2
SMILES	C=CC(NC1=CC=C(N2)C(N(C3CCN(CC4=CC=C(C5=NC6=C(C(NC=C6)=O)C=C5C7=CC=CC=C7)C=C4)CC3)C2=O)=C1)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	95 mg/mL (159.21 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.76 mL	83.8 mL	167.59 mL
0.5 mM	3.35 mL	16.76 mL	33.52 mL
1 mM	1.68 mL	8.38 mL	16.76 mL
5 mM	0.34 mL	1.68 mL	3.35 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Product Name	Price	Stock
Borussertib 5mg	$270.00	In stock
Borussertib 10mg	$465.00	In stock
Borussertib 50mg	$1,380.00	In stock
Borussertib 100mg	$2,760.00	In stock