BQ-788 is a selective endothelin B (ETB) receptor antagonist, exhibiting a potent IC50 of 1.2 nM against endothelin-1 (ET-1) binding in human Girardi heart cells. It demonstrates limited inhibitory activity on ETA receptors in the human neuroblastoma SK-N-MC cell line, with an IC50 of 1300 nM. This compound is primarily utilized in research on cardiovascular and neurobiological systems, aimed at elucidating the role of ETB receptors in various physiological and pathological conditions.
BQ-788 is a selective endothelin B (ETB) receptor antagonist, exhibiting a potent IC50 of 1.2 nM against endothelin-1 (ET-1) binding in human Girardi heart cells. It demonstrates limited inhibitory activity on ETA receptors in the human neuroblastoma SK-N-MC cell line, with an IC50 of 1300 nM. This compound is primarily utilized in research on cardiovascular and neurobiological systems, aimed at elucidating the role of ETB receptors in various physiological and pathological conditions.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
