Br-C10-methyl ester serves as a critical linker in the design of PROTAC molecules, characterized by its alkyl/ether composition. This compound facilitates the assembly of PROTACs, such as MS432, by bridging distinct ligands: one that targets the VHL E3 ubiquitin ligase and another that binds to the protein of interest. Its use enables targeted protein degradation, making it essential in biomedical research and therapeutic development.
Br-C10-methyl ester serves as a critical linker in the design of PROTAC molecules, characterized by its alkyl/ether composition. This compound facilitates the assembly of PROTACs, such as MS432, by bridging distinct ligands: one that targets the VHL E3 ubiquitin ligase and another that binds to the protein of interest. Its use enables targeted protein degradation, making it essential in biomedical research and therapeutic development.
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