Brincidofovir (CMX001)

Catalog No.: A13326

Brincidofovir (CMX001)

Brincidofovir (CMX001) Chemical Structure

CAS NO. 444805-28-1

Brincidofovir is a prodrug of cidofovir. Conjugated to a lipid, the compound is designed to release cidofovir intracellularly, allowing for higher intracellular and lower plasma concentrations of cidofovir, effectively increasing its activity against dsDNA viruses, as well as oral bioavailability.

Availability: In stock

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5 mg

Regular Price: $580.00

Special Price $464.00

10 mg

Regular Price: $1,100.00

Special Price $880.00

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Biological Activity

Brincidofovir is a prodrug of cidofovir. Conjugated to a lipid, the compound is designed to release cidofovir intracellularly, allowing for higher intracellular and lower plasma concentrations of cidofovir, effectively increasing its activity against dsDNA viruses, as well as oral bioavailability.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.8 mL 89.02 mL 178.03 mL
0.5 mM 3.56 mL 17.8 mL 35.61 mL
1 mM 1.78 mL 8.9 mL 17.8 mL
5 mM 0.36 mL 1.78 mL 3.56 mL

*The above data is based on the productmolecular weight 561.7008. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13326
CAS No. 444805-28-1
Formula C27H52N3O7P
M. Wt 561.7008
Purity >98%
Synonyms CMX001, Cidofovir-HDP, hexadecyloxypropyl-cidofovir
SMILES CCCCCCCCCCCCCCCCOCCCOP(=O)(CO[[email protected]@H](CN1C=CC(=NC1=O)N)CO)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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