Bromo-PEG4-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with compounds containing alkyne functionality. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties. This versatility makes Bromo-PEG4-azide a valuable tool for researchers involved in targeted protein degradation studies.
Bromo-PEG4-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with compounds containing alkyne functionality. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties. This versatility makes Bromo-PEG4-azide a valuable tool for researchers involved in targeted protein degradation studies.
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