Bromo-PEG6-azide is a PEG-based linker designed for use in the synthesis of PROTACs, targeting protein degradation pathways. This compound features an azide group enabling its functionality as a click chemistry reagent, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized entities, facilitating efficient conjugation in various chemical biology applications.
Bromo-PEG6-azide is a PEG-based linker designed for use in the synthesis of PROTACs, targeting protein degradation pathways. This compound features an azide group enabling its functionality as a click chemistry reagent, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized entities, facilitating efficient conjugation in various chemical biology applications.
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