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BTT-266

Catalog No.: A66082
Calcium Channel Antagonist
BTT-266 is a calcium channel antagonist that functions by inhibiting the interaction between CaVα1-AID and CaVβ3, exhibiting a Ki value of 1.4 μM. It effectively modulates the activation of voltage-dependent CaV2.2 channels. BTT-266 demonstrates analgesic properties in models of neuropathic pain, making it a valuable tool for research into pain modulation and potential therapeutic applications.
BTT-266 2413939-89-4 Calcium Channel Antagonist
Grouped product items
Size Price Stock Qty
1mg
$55.00
In stock
5mg
$130.00
In stock
10mg
$200.00
In stock
25mg
$350.00
In stock
50mg
$520.00
In stock
100mg
$760.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBTT-266 is a calcium channel antagonist that functions by inhibiting the interaction between CaVα1-AID and CaVβ3, exhibiting a Ki value of 1.4 μM. It effectively modulates the activation of voltage-dependent CaV2.2 channels. BTT-266 demonstrates analgesic properties in models of neuropathic pain, making it a valuable tool for research into pain modulation and potential therapeutic applications.
Product Information
Catalog NumA66082
FormulaC34H28N4O4
Molecular Weight556.61
CAS Number2413939-89-4
SMILESO=C(C1=CC=CC(C(N2N=C(CC2C3=CN(C4=CC=CC=C4)N=C3C5=CC=C(C)C=C5)C6=CC=C(OC)C=C6)=O)=C1)O
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Membrane Transporters-Ion Channels > Calcium Channels