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Biological Activity
BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), with MICs of of 2.3 nM and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.18 mL | 115.9 mL | 231.81 mL |
| 0.5 mM | 4.64 mL | 23.18 mL | 46.36 mL |
| 1 mM | 2.32 mL | 11.59 mL | 23.18 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.64 mL |
*The above data is based on the productmolecular weight 431.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21263 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1161233-85-7 |
| Formula | C17H16F3N3O5S |
| M. Wt | 431.39 |
| Purity | >98% |
| SMILES | O=C1N=C(N(CC2)CCC32OC[[email protected]](C)O3)SC4=C([N+]([O-])=O)C=C(C(F)(F)F)C=C14 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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