BZX2 is an irreversible covalent inhibitor of O-GlcNAc transferase (OGT), demonstrating an IC50 of less than 10 µM. This compound is cell-permeable, allowing for effective intracellular delivery, though it may exhibit multiple off-target effects. BZX2 is primarily utilized in research applications focused on OGT-related signaling pathways and O-GlcNAcylation processes in various biological contexts.
BZX2 is an irreversible covalent inhibitor of O-GlcNAc transferase (OGT), demonstrating an IC50 of less than 10 µM. This compound is cell-permeable, allowing for effective intracellular delivery, though it may exhibit multiple off-target effects. BZX2 is primarily utilized in research applications focused on OGT-related signaling pathways and O-GlcNAcylation processes in various biological contexts.
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