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$0.00 Biological Activity
c-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.19 mL | 75.94 mL | 151.88 mL |
| 0.5 mM | 3.04 mL | 15.19 mL | 30.38 mL |
| 1 mM | 1.52 mL | 7.59 mL | 15.19 mL |
| 5 mM | 0.3 mL | 1.52 mL | 3.04 mL |
*The above data is based on the productmolecular weight 658.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21823 |
|---|---|
| Actions | Agonist |
| CAS No. | 54447-84-6 |
| Formula | C20H24N10O12P2 |
| M. Wt | 658.41 |
| Purity | >98% |
| Synonyms | Cyclic diadenylate; Cyclic-di-AMP |
| SMILES | O[[email protected]]([[email protected]@](OP(O)(OC[[email protected]](O[[email protected]@H](N1C2=NC=NC(N)=C2N=C1)[[email protected]@H]3O)([H])[[email protected]@]3([H])O4)=O)([H])[[email protected]](COP4(O)=O)([H])O5)[[email protected]@H]5N6C7=NC=NC(N)=C7N=C6 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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