CAB7-3 is an orally active capsid assembly modulator targeting Hepatitis B Virus (HBV), exhibiting potent antiviral activity. It demonstrates significant efficacy with EC50 values of 70 nM in HepDES19 cells, 1 nM in HepAD38 cells, and 2 nM in HBV-infected HLCZ01 cells. CAB7-3 effectively reduces hepatic HBV core protein levels and suppresses viral replication in vivo. This compound is valuable for research aimed at understanding and treating HBV infections.
CAB7-3 is an orally active capsid assembly modulator targeting Hepatitis B Virus (HBV), exhibiting potent antiviral activity. It demonstrates significant efficacy with EC50 values of 70 nM in HepDES19 cells, 1 nM in HepAD38 cells, and 2 nM in HBV-infected HLCZ01 cells. CAB7-3 effectively reduces hepatic HBV core protein levels and suppresses viral replication in vivo. This compound is valuable for research aimed at understanding and treating HBV infections.
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