Cabozantinib-d4 is a deuterium-labeled analog of Cabozantinib, which functions as a potent inhibitor of multiple receptor tyrosine kinases (RTKs). It exhibits significant inhibition of VEGFR2, c-Met, Kit, Axl, and Flt3 with IC50 values of 0.035 nM, 1.3 nM, 4.6 nM, 7 nM, and 11.3 nM, respectively. This stabilized isotope is valuable for pharmacokinetic and metabolic studies, enabling researchers to trace and analyze the drug's metabolic pathways and interactions in biological systems.
Cabozantinib-d4 is a deuterium-labeled analog of Cabozantinib, which functions as a potent inhibitor of multiple receptor tyrosine kinases (RTKs). It exhibits significant inhibition of VEGFR2, c-Met, Kit, Axl, and Flt3 with IC50 values of 0.035 nM, 1.3 nM, 4.6 nM, 7 nM, and 11.3 nM, respectively. This stabilized isotope is valuable for pharmacokinetic and metabolic studies, enabling researchers to trace and analyze the drug's metabolic pathways and interactions in biological systems.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
