CAL-101 (GS-1101, Idelalisib)

CAL-101 is an isoform-selective inhibitor of PI3K that induces apoptosis of chronic lymphocytic leukemia (CLL) cells.
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Product Name Price Stock Qty
CAL-101 10mg
Special Price $32.00 Regular Price $40.00
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CAL-101 25mg
Special Price $72.00 Regular Price $90.00
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CAL-101 50mg
Special Price $128.00 Regular Price $160.00
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CAL-101 100mg
Special Price $240.00 Regular Price $300.00
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CAL-101 (GS-1101) 10mM * 1mL in DMSO
Special Price $60.80 Regular Price $76.00
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Adooq Products cited in reputable paper
Adooq's CAL-101 (GS-1101, Idelalisib) has been cited by 4 publications
  • Ming-Chun Hung, .et al. , Cell Biosci, 2022, 12: 122 PMID: 35918763
  • Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
  • Pridham KJ, .et al. , Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844
  • Yoshihiro Umezawa, .et al. , J Biol Chem, 2017, Dec 1; 292(48): 19639-19655 PMID: 28974577
  • Biological Activity
    Discription CAL-101 is an isoform-selective inhibitor of PI3K that induces apoptosis of chronic lymphocytic leukemia (CLL) cells.
    Targets
    Target Value
    Product Information
    Catalog Num A10172
    Formula C22H18FN7O
    Molecular Weight 415.4
    CAS Number 870281-82-6
    SMILES CC[C@@H](C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 76 mg/mL (182.94 mM)
    Water Insoluble
    Ethanol 21 mg/mL (50.55 mM)
    In vivo 2% DMSO+20%PEG 300+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.07 mL 120.37 mL 240.73 mL
    0.5 mM 4.81 mL 24.07 mL 48.15 mL
    1 mM 2.41 mL 12.04 mL 24.07 mL
    5 mM 0.48 mL 2.41 mL 4.81 mL
    Useful Calculator

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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