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$0.00 Biological Activity
Calyculin A is a potent and cell-permeable protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC50s of 2 nM and 0.5-1 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 9.91 mL | 49.55 mL | 99.09 mL |
| 0.5 mM | 1.98 mL | 9.91 mL | 19.82 mL |
| 1 mM | 0.99 mL | 4.95 mL | 9.91 mL |
| 5 mM | 0.2 mL | 0.99 mL | 1.98 mL |
*The above data is based on the productmolecular weight 1009.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11791 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 1009.17 |
| Formula | C50H81N4O15P |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 101932-71-2 |
| Synonyms | (-)-Calyculin A |
| SMILES | O[[email protected]@H]([[email protected]]([[email protected]@H](N(C)C)COC)O)C(NCC[[email protected]@H](C1=NC(/C=C/C[[email protected]@H]([[email protected]@H](C)[[email protected]](O)C2)O[[email protected]@]32C(C)(C)[[email protected]@H](OP(O)(O)=O)[[email protected]@H]([[email protected]@H](OC)C[[email protected]](O)[[email protected]](C)[[email protected]](O)[[email protected]](C)/C=C(C)/C(C)=C/C=C/C(C)=C\C#N)O3)=CO1)C)=O |
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