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  1. Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase).
  2. protein tyrosine phosphatases inhibitor

    Sodium orthovanadate is the chemical compound Na3VO4. It is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.
  3. Phosphatase inhibitor

    NSC 95397 is a selective and effective dual-specificity, quinone-based phosphatase inhibitor.
  4. PP2A inhibitor

    LB-100 is a small-molecular protein phosphatase 2A(PP2A)inhibitor with IC50 of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
  5. PPP1R15A inhibitor

    Sephin1 is a selective inhibitor of stress-induced PPP1R15A and targets disease associated with accumulation of misfolded protein.
  6. PP1 inhibitor

    Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells.
  7. phosphatase inhibitor

    (-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.
  8. CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM.
  9. eIF2α phosphatase inhibitor

    Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor.
  10. protein phosphatase inhibitor

    Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
  11. Ser/Thr protein phosphatase activator

    Ceramide is a ceramide shown to be a potent modulator of proliferation and differentiation, used as a tool for studying the complex signaling associated with the ceramides.
  12. serine/threonine phosphatase inhibitor

    Fumonisin B1 is a fungal metabolite produced by Fusarium moniliforme, that has been shown to inhibit protein serine/threonine phosphatases (PP1, PP2A, PP2B, PP2C, and PP5/T/K/H), and is most effective with PP5.
  13. Wip1 phosphatase inhibitor

    GSK 2830371 is a highly selective Wip1 phosphatase inhibitor with IC50 of 6 nM.
  14. Eukaryotic ribosome biogenesis inhibitor

    Rbin-1 is a potent, reversible, and specific chemical inhibitor of eukaryotic ribosome biogenesis. Rbin-1 inhibits the ATPase with GI50 of 136 nM. Rbin-1 is a potent and selective chemical inhibitor of Midasin (Mdn1).
  15. PP2A activator

    SMAP-2 (DT-1154) is an orally bioavailable phosphatase 2A (PP2A) activator which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A.
  16. PPP1R15B inhibitor

    Raphin1 is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B).
  17. pan-PHLPP inhibitor

    NSC-45586 is a pan-PHLPP inhibitor selective for PHLPP1 and PHLPP2.
  18. DDHD2 inhibitor

    KLH45 is a potent and selective DDHD2 inhibitor, with an IC50 of 1.3 nM.

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