Canagliflozin
Canagliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2).
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Adooq Products cited in reputable paper
Adooq's Canagliflozin has been cited by 5 publications
- Ming-Jer Hsieh, .et al. , Naunyn Schmiedebergs Arch Pharmacol, 2025, Apr 30 PMID: 40304747
- Courtney Sakolish, .et al. , Biomedicines, 2025, 13(3), 563
- Jing Zhou, .et al. , Exp Mol Med, 2022, Nov; 54(11): 2007-2021 PMID: 36385558
- David Papadopoli, .et al. , Neoplasia, 2021, Apr;23(4):391-399 PMID: 33784591
- Angelopoulou A, .et al. , Nanomedicine, 2018, Oct;13(19):2435-2454 PMID: 30311542
Biological Activity
| Description | Canagliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2). | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A11100 |
|---|---|
| Formula | C24H25FO5S |
| Molecular Weight | 444.5 |
| CAS Number | 842133-18-0 |
| SMILES | CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 79 mg/mL (177.71 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 0.5% CMC+0.25% Tween 80 | 17 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.5 mL | 112.49 mL | 224.97 mL |
| 0.5 mM | 4.5 mL | 22.5 mL | 44.99 mL |
| 1 mM | 2.25 mL | 11.25 mL | 22.5 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.5 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
