Canagliflozin

Catalog No.: A11100
SGLT2 Inhibitor
Canagliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2).
Grouped product items
Product Name Price Stock Qty
Canagliflozin 5mg
$50.00
In stock
Canagliflozin 10mg
$70.00
In stock
Canagliflozin 50mg
$100.00
In stock
Canagliflozin 100mg
$125.00
In stock
Canagliflozin 10mM * 1mL in DMSO
$55.00
In stock
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Adooq Products cited in reputable paper
Adooq's Canagliflozin has been cited by 3 publications
  • Jing Zhou, .et al. , Exp Mol Med, 2022, Nov; 54(11): 2007-2021 PMID: 36385558
  • David Papadopoli, .et al. , Neoplasia, 2021, Apr;23(4):391-399 PMID: 33784591
  • Angelopoulou A, .et al. , Nanomedicine, 2018, Oct;13(19):2435-2454 PMID: 30311542
  • Biological Activity
    Discription Canagliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2).
    Targets
    Target Value
    Product Information
    Catalog Num A11100
    Formula C24H25FO5S
    Molecular Weight 444.5
    CAS Number 842133-18-0
    SMILES CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 79 mg/mL (177.71 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% CMC+0.25% Tween 80 17 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.5 mL 112.49 mL 224.97 mL
    0.5 mM 4.5 mL 22.5 mL 44.99 mL
    1 mM 2.25 mL 11.25 mL 22.5 mL
    5 mM 0.45 mL 2.25 mL 4.5 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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