Cavα2δ1&NET-IN-2 is a dual inhibitor targeting the α2δ-1 subunit of voltage-gated calcium channels and the norepinephrine transporter (NET). It demonstrates effective inhibition of Cavα2δ-1 with a Ki of 454 nM and exhibits potent inhibition of NET with a Ki of 59 nM and an IC50 of 7 nM. This compound is valuable for research focused on pain mechanisms and the associated neurotransmitter systems.
Cavα2δ1&NET-IN-2 is a dual inhibitor targeting the α2δ-1 subunit of voltage-gated calcium channels and the norepinephrine transporter (NET). It demonstrates effective inhibition of Cavα2δ-1 with a Ki of 454 nM and exhibits potent inhibition of NET with a Ki of 59 nM and an IC50 of 7 nM. This compound is valuable for research focused on pain mechanisms and the associated neurotransmitter systems.
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