Cbz-NH-PEG3-tosyl

Catalog No.: A84329
PROTAC Linker
Cbz-NH-PEG3-tosyl is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its polyethylene glycol (PEG) spacer enhances solubility and flexibility, facilitating efficient conjugation to various target proteins and E3 ligases. This linker is essential for developing novel therapeutic strategies in targeted protein degradation research.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCbz-NH-PEG3-tosyl is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its polyethylene glycol (PEG) spacer enhances solubility and flexibility, facilitating efficient conjugation to various target proteins and E3 ligases. This linker is essential for developing novel therapeutic strategies in targeted protein degradation research.
Product Information
Catalog NumA84329
FormulaC21H27NO7S
Molecular Weight437.51
CAS Number2098983-15-2
SMILESO=C(OCC=1C=CC=CC1)NCCOCCOCCOS(=O)(=O)C2=CC=C(C=C2)C
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