Cbz-PEG4-NH2

Catalog No.: A84312
PROTAC Linker
Cbz-PEG4-NH2 is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins by linking a ligand to an E3 ligase, thereby enabling targeted protein modulation. Its application in PROTAC development is crucial for advancing research in targeted therapy and understanding protein dynamics within cellular systems.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCbz-PEG4-NH2 is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins by linking a ligand to an E3 ligase, thereby enabling targeted protein modulation. Its application in PROTAC development is crucial for advancing research in targeted therapy and understanding protein dynamics within cellular systems.
Product Information
Catalog NumA84312
FormulaC18H30N2O6
Molecular Weight370.45
CAS Number2708281-05-2
SMILESO=C(OCC=1C=CC=CC1)NCCOCCOCCOCCOCCN
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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