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- Jacob Insua-Rodr??guez, .et al. Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis, EMBO Mol Med, 2018, Oct; 10(10): e9003 PMID: 30190333
Biological Activity
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.74 mL | 128.7 mL | 257.4 mL |
| 0.5 mM | 5.15 mL | 25.74 mL | 51.48 mL |
| 1 mM | 2.57 mL | 12.87 mL | 25.74 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.15 mL |
*The above data is based on the productmolecular weight 388.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11352 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 395104-30-0 |
| Formula | C22H24N6O |
| M. Wt | 388.5 |
| Purity | >98% |
| Synonyms | CC401 |
| SMILES | C1CCN(CC1)CCOC2=CC=CC(=C2)C3=NNC4=C3C=C(C=C4)C5=NC=NN5 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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