CCT137690

Catalog No.: A11081
Aurora Kinase inhibitor
CCT137690 is a highly selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 15 nM, 25 nM and 19 nM. It has little effect on hERG ion-channel.
Grouped product items
Product Name Price Stock Qty
CCT137690 5mg
Special Price $68.00 Regular Price $85.00
In stock
CCT137690 10mg
Special Price $88.00 Regular Price $110.00
In stock
CCT137690 50mg
Special Price $320.00 Regular Price $400.00
In stock
CCT137690 100mg
Special Price $500.00 Regular Price $625.00
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Biological Activity
Discription CCT137690 is a highly selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 15 nM, 25 nM and 19 nM. It has little effect on hERG ion-channel.
Targets
Target Value
Product Information
Catalog Num A11081
Formula C26H31BrN8O
Molecular Weight 551.5
CAS Number 1095382-05-0
SMILES CC1=CC(=NO1)CN2CCN(CC2)C3=C4C(=NC=C3Br)N=C(N4)C5=CC=C(C=C5)N6CCN(CC6)C
Synonyms CCT-137690
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 4 mg/mL (7.25 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.13 mL 90.66 mL 181.32 mL
0.5 mM 3.63 mL 18.13 mL 36.26 mL
1 mM 1.81 mL 9.07 mL 18.13 mL
5 mM 0.36 mL 1.81 mL 3.63 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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