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Aurora Kinase inhibitor

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Catalog No. A11081

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CCT137690 5mg A11081-5
CCT137690 10mg A11081-10
CCT137690 50mg A11081-50
CCT137690 100mg A11081-100

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CCT137690 is a highly selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 15 nM, 25 nM and 19 nM. It has little effect on hERG ion-channel.


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Chemical Information

Catalog Num A11081
Actions Inhibitor
M. Wt 551.5
Formula C26H31BrN8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1095382-05-0
Synonyms CCT-137690

Biological Activity

CCT137690 is a highly selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 15 nM, 25 nM and 19 nM. It has little effect on hERG ion-channel.
Aurora A Aurora C Aurora B
15 nM19 nM25 nM


Solubility (25°C) * In vitro DMSO 4 mg/mL (7.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.13 mL 90.66 mL 181.32mL
0.5 mM 3.63 mL 18.13 mL 36.26 mL
1 mM 1.81 mL 9.07 mL 18.13 mL
5 mM 0.36 mL 1.81 mL 3.63 mL

*The above data is based on the productmolecular weight 551.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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