Cemadotin hydrochloride

Catalog No.: A54922
Tubulin Inhibitor
Cemadotin hydrochloride is a potent tubulin inhibitor that disrupts microtubule dynamics, leading to cell cycle arrest in the mitotic phase. With a Ki value of 1 μM, it effectively inhibits cell proliferation in vitro and reduces tumor xenograft growth in murine models. This compound is an important tool for investigating anticancer mechanisms and potential therapeutic applications in cancer research.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCemadotin hydrochloride is a potent tubulin inhibitor that disrupts microtubule dynamics, leading to cell cycle arrest in the mitotic phase. With a Ki value of 1 μM, it effectively inhibits cell proliferation in vitro and reduces tumor xenograft growth in murine models. This compound is an important tool for investigating anticancer mechanisms and potential therapeutic applications in cancer research.
Product Information
Catalog NumA54922
FormulaC35H57ClN6O5
Molecular Weight677.32
CAS Number172837-41-1
SMILESCl.CC(C)[C@H](NC(=O)[C@H](C(C)C)N(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1
SynonymsLU103793 hydrochloride
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