Ceratotoxin-2 is a potent blocker of voltage-gated sodium channels, exhibiting IC50 values of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively. This compound is valuable for investigating sodium channel-related physiological processes and studying disorders associated with sodium channel dysfunction. Its high specificity makes it an essential tool for research in neurobiology and pharmacology, facilitating the development of targeted therapies.
Ceratotoxin-2 is a potent blocker of voltage-gated sodium channels, exhibiting IC50 values of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively. This compound is valuable for investigating sodium channel-related physiological processes and studying disorders associated with sodium channel dysfunction. Its high specificity makes it an essential tool for research in neurobiology and pharmacology, facilitating the development of targeted therapies.
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