CH2Br-Bicyclo1.1.1pentane-COOH

Catalog No.: A82912
PROTAC Linker
CH2Br-Bicyclo[1.1.1]pentane-COOH is a versatile PROTAC linker designed to facilitate the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound serves as a crucial component in the development of targeted protein degradation strategies, enabling researchers to selectively modulate protein levels within cells. Its unique structural characteristics enhance the effectiveness and specificity of PROTACs in various biological applications, making it a valuable tool in chemical biology and drug discovery.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCH2Br-Bicyclo[1.1.1]pentane-COOH is a versatile PROTAC linker designed to facilitate the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound serves as a crucial component in the development of targeted protein degradation strategies, enabling researchers to selectively modulate protein levels within cells. Its unique structural characteristics enhance the effectiveness and specificity of PROTACs in various biological applications, making it a valuable tool in chemical biology and drug discovery.
Product Information
Catalog NumA82912
FormulaC7H9BrO2
Molecular Weight205.05
CAS Number2742661-04-5
SMILESO=C(O)C12CC(CBr)(C1)C2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2