CH2COOH-PEG6-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis targeting chimeras). This compound facilitates the conjugation of target proteins and E3 ligase, enhancing the degradation of specific proteins through the ubiquitin-proteasome pathway. Its application is significant in drug discovery research, particularly in the development of targeted protein degradation therapies.
CH2COOH-PEG6-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis targeting chimeras). This compound facilitates the conjugation of target proteins and E3 ligase, enhancing the degradation of specific proteins through the ubiquitin-proteasome pathway. Its application is significant in drug discovery research, particularly in the development of targeted protein degradation therapies.
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