CHF 4227 free base is a selective estrogen receptor modulator (SERM) that exhibits high affinity for both human estrogen receptor-α and -β, with Ki values of 0.017 nM and 0.099 nM, respectively. This compound demonstrates significant biological activity in modulating estrogen-related pathways, making it valuable for research in hormone-dependent tumors and other estrogen-related diseases. Its oral bioavailability allows for convenient administration in various preclinical studies.
CHF 4227 free base is a selective estrogen receptor modulator (SERM) that exhibits high affinity for both human estrogen receptor-α and -β, with Ki values of 0.017 nM and 0.099 nM, respectively. This compound demonstrates significant biological activity in modulating estrogen-related pathways, making it valuable for research in hormone-dependent tumors and other estrogen-related diseases. Its oral bioavailability allows for convenient administration in various preclinical studies.
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