CHIR-99021 monohydrochloride

Catalog No.: A21430

GSK-3α/β inhibitor

CHIR-99021 monohydrochloride

CHIR-99021 monohydrochloride Chemical Structure

CAS NO. 1797989-42-4

CHIR-99021 monohydrochloride (CT99021 monohydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases.

Availability: In stock

Package Price Qty
5 mg
$72.00
10 mg
$124.00
50 mg
$368.00
100 mg
$736.00
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Biological Activity

CHIR-99021 monohydrochloride (CT99021 monohydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.93 mL 99.64 mL 199.28 mL
0.5 mM 3.99 mL 19.93 mL 39.86 mL
1 mM 1.99 mL 9.96 mL 19.93 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21430
Actions Inhibitor
M. Wt 501.8
Formula C22H19Cl3N8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1797989-42-4
Synonyms CHIR99021, CHIR 99021, CT99021 monohydrochloride, CT 99021, CT-99021
SMILES N#CC1=CC=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)N=C1.[H]Cl

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