The store will not work correctly in the case when cookies are disabled.
JavaScript seems to be disabled in your browser.
For the best experience on our site, be sure to turn on Javascript in your browser.
Laduviglusib (CHIR-99021)
Catalog No.: A10199
GSK-3 Inhibitor
CHIR99021 is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively.
Adooq Products cited in reputable paper
Adooq's Laduviglusib (CHIR-99021) has been cited by 13 publications
Peilin Li, .et al. , Ecotoxicol Environ Saf , 2024, Dec:288:117330 PMID: 39571255 Peilin Li, .et al. , Stem Cell Res Ther , 2024, Aug 26;15(1):269 PMID: 39183353 Andreea Manole, .et al. , Cell Rep , 2023, Dec 26;42(12):113466 PMID: 38039131 Claudia Z Han, .et al. , Immunity , 2023, Sep 12;56(9):2152-2171 PMID: 37582369 Eric Lian, .et al. , STAR Protoc , 2023, May 22;4(2):102314 PMID: 37220001 Tomoki Murata, .et al. , Int Immunol , 2023, Apr 13 PMID: 37052267 Shunsuke Murakami, .et al. , Regen Ther , 2022, Nov 25;21:574-583 PMID: 36475025 Adam Pietrobon, .et al. , Cell Rep , 2022, Jul 5;40(1):111048 PMID: 35793620 Takayuki Miyoshi, .et al. , J Gastroenterol , 2022, Jun;57(6):441-452 PMID: 35294680 Tomoki Kamatani, .et al. , Inflamm Regen , 2022, Feb 2;42(1):4 PMID: 35105370 Dan Zhao, .et al. , Poult Sci , 2022, Mar; 101(3): 101642 PMID: 35016046 Otsuka R, .et al. , Sci Rep , 2020, Jan 14;10(1):224 PMID: 31937817 Yu Huang, .et al. , Stem Cells Int , 2019, 2019: 3975689 PMID: 31565060
Biological Activity
Discription
CHIR99021 is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively.
Targets
Cell Research
Cell Line
Type
Value
Description
References
Solubility
In vitro (25°C)
DMSO
Warmed: 9 mg/mL (19.33 mM)
Water
Insoluble
Ethanol
Insoluble
In vivo
4% DMSO+30% PEG 300+ddH2O
3.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass
1 mg
5 mg
10 mg
0.1 mM
21.49 mL
107.46 mL
214.92 mL
0.5 mM
4.3 mL
21.49 mL
42.98 mL
1 mM
2.15 mL
10.75 mL
21.49 mL
5 mM
0.43 mL
2.15 mL
4.3 mL
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
* Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1 V1 = C2 V2
Keywords: buy Laduviglusib (CHIR-99021) | Laduviglusib (CHIR-99021) Supplier | purchase Laduviglusib (CHIR-99021) | Laduviglusib (CHIR-99021) cost | Laduviglusib (CHIR-99021) manufacturer | order Laduviglusib (CHIR-99021) | Laduviglusib (CHIR-99021) distributor
| buy 252917-06-9 | 252917-06-9 Supplier | purchase 252917-06-9 | 252917-06-9 cost | 252917-06-9 manufacturer | order 252917-06-9 | 252917-06-9 distributor