CHIR-99021

Catalog No.: A10199

GSK-3 Inhibitor

CHIR-99021

CHIR-99021 Chemical Structure

CAS NO. 252917-06-9

CHIR99021 is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively.

Availability: In stock

Package Price Qty
2 mg

Regular Price: $50.00

Special Price $40.00

5 mg

Regular Price: $70.00

Special Price $56.00

25 mg

Regular Price: $210.00

Special Price $168.00

100 mg

Regular Price: $550.00

Special Price $440.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

CHIR99021 is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively.
Targets
GSK-3β GSK-3α
6.7 nM10 nM
In vitro DMSO 78 mg/mL warmed (167.61 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.49 mL 107.46 mL 214.92 mL
0.5 mM 4.3 mL 21.49 mL 42.98 mL
1 mM 2.15 mL 10.75 mL 21.49 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10199
Actions Inhibitor
M. Wt 465.3
Formula C22H18Cl2N8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 252917-06-9
Synonyms GSK-3 Inhibitor XVI, CT 99021, CHIR99021
SMILES CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy CHIR-99021 | CHIR-99021 Supplier | purchase CHIR-99021 | CHIR-99021 cost | CHIR-99021 manufacturer | order CHIR-99021 | CHIR-99021 distributor | buy 252917-06-9| 252917-06-9 Supplier | purchase 252917-06-9 | 252917-06-9 cost | 252917-06-9 manufacturer | order 252917-06-9 | 252917-06-9 distributor
Rewards