Chlormezanone (Trancopal)

Catalog No.: A10201

Chlormezanone (Trancopal)

Chlormezanone (Trancopal) Chemical Structure

CAS NO. 80-77-3

Chlormezanone (Trancopal), a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm. Chlormezanone binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmitter GABA, increasing the inhibition of the ascending reticular activating system and blocking the cortical and limbic arousal that occurs following stimulation of the reticular pathways.

Availability: In stock

Package Price Qty
50 mg
$30.00
100 mg
$45.00
10mM * 1mL in DMSO
$50.00
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Biological Activity

Chlormezanone (Trancopal), a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm. Chlormezanone binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmitter GABA, increasing the inhibition of the ascending reticular activating system and blocking the cortical and limbic arousal that occurs following stimulation of the reticular pathways.
Targets
In vitro DMSO 55 mg/mL (200.92 mM)
Water <1 mg/mL (<1 mM)
Ethanol 26 mg/mL (94.98 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.54 mL 182.68 mL 365.36 mL
0.5 mM 7.31 mL 36.54 mL 73.07 mL
1 mM 3.65 mL 18.27 mL 36.54 mL
5 mM 0.73 mL 3.65 mL 7.31 mL

*The above data is based on the productmolecular weight 273.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10201
M. Wt 273.7
Formula C11H12ClNO3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 80-77-3
Synonyms Trancopal
SMILES CN1C(S(=O)(=O)CCC1=O)C2=CC=C(C=C2)Cl

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