CHZ868

Catalog No.: A15937

JAK2 inhibitor

CHZ868

CHZ868 Chemical Structure

CAS NO. 1895895-38-1

CHZ868 is a potent and selective type II JAK inhibitor which demonstrates activity in JAK inhibitor persistent cells, murine MPN models, and MPN patient samples.

Availability: In stock

Package Price Qty
2 mg
$80.00
5 mg
$130.00
10 mg
$210.00
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Biological Activity

CHZ868 is a potent and selective type II JAK inhibitor which demonstrates activity in JAK inhibitor persistent cells, murine MPN models, and MPN patient samples.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.62 mL 118.09 mL 236.17 mL
0.5 mM 4.72 mL 23.62 mL 47.23 mL
1 mM 2.36 mL 11.81 mL 23.62 mL
5 mM 0.47 mL 2.36 mL 4.72 mL

*The above data is based on the productmolecular weight 423.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15937
Actions Inhibitor
CAS No. 1895895-38-1
Formula C22H19F2N5O2
M. Wt 423.42
Solubility DMSO
Purity >98%
Synonyms CHZ 868, CHZ-868
SMILES CC(NC1=NC=CC(OC2=CC=C3N(C)C(NC4=CC=C(F)C=C4F)=NC3=C2C)=C1)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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