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CHZ868

JAK2 inhibitor

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Catalog No. A15937

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CHZ868 2mg A15937-2
$90.00
CHZ868 5mg A15937-5
$180.00
CHZ868 10mg A15937-10
$300.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CHZ868 is a potent and selective type II JAK inhibitor which demonstrates activity in JAK inhibitor persistent cells, murine MPN models, and MPN patient samples.

CHZ868

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Chemical Information

Catalog Num A15937
Actions Inhibitor
M. Wt 423.42
Formula C22H19F2N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1895895-38-1
Synonyms CHZ 868, CHZ-868
SMILES CC(NC1=NC=CC(OC2=CC=C3N(C)C(NC4=CC=C(F)C=C4F)=NC3=C2C)=C1)=O

Biological Activity

Description
CHZ868 is a potent and selective type II JAK inhibitor which demonstrates activity in JAK inhibitor persistent cells, murine MPN models, and MPN patient samples.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.62 mL 118.09 mL 236.17mL
0.5 mM 4.72 mL 23.62 mL 47.23 mL
1 mM 2.36 mL 11.81 mL 23.62 mL
5 mM 0.47 mL 2.36 mL 4.72 mL

*The above data is based on the productmolecular weight 423.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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