CI 972

Catalog No.: A18598

PNP inhibitor

CI 972

CI 972 Chemical Structure

CAS NO. 115787-68-3

CI 972 is a potent, orally active, and competitive inhibitor of purine nucleoside phosphorylase (PNP) (Ki=0.83 μM) under development as a T cell-selective immunosuppressive agent.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

CI 972 is a potent, orally active, and competitive inhibitor of purine nucleoside phosphorylase (PNP) (Ki=0.83 μM) under development as a T cell-selective immunosuppressive agent.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.58 mL 167.92 mL 335.84 mL
0.5 mM 6.72 mL 33.58 mL 67.17 mL
1 mM 3.36 mL 16.79 mL 33.58 mL
5 mM 0.67 mL 3.36 mL 6.72 mL

*The above data is based on the productmolecular weight 297.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18598
Actions Inhibitor
CAS No. 115787-68-3
Formula C11H12ClN5OS
M. Wt 297.76
Purity >98%
Synonyms CI 972; CI972; CI-972.
SMILES c1([nH]c2c(c(n1)=O)[nH]c(c2Cc1cscc1)N)N.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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