CI 972 is a potent, orally active, and competitive inhibitor of purine nucleoside phosphorylase (PNP) (Ki=0.83 μM) under development as a T cell-selective immunosuppressive agent.
CI 972 is a potent, orally active, and competitive inhibitor of purine nucleoside phosphorylase (PNP) (Ki=0.83 μM) under development as a T cell-selective immunosuppressive agent.
Product Information
Catalog Num
A18598
Formula
C11H12ClN5OS
Molecular Weight
297.76
CAS Number
115787-68-3
SMILES
c1([nH]c2c(c(n1)=O)[nH]c(c2Cc1cscc1)N)N.Cl
Synonyms
CI 972; CI972; CI-972.
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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