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$0.00 - Katsuhisa Morita, .et al. Decomposition profile data analysis of multiple drug effects identifies endoplasmic reticulum stress-inducing ability as an unrecognized factor, Sci Rep, 2020, 10: 13139 PMID: 32753643
Biological Activity
Ciclopirox is currently being investigated as an alternative treatment to ketoconazole for seborrhoeic dermatitis as it suppresses growth of the yeast Malassezia furfur.It acts by inhibiting the membrane transfer system by interrupting the Na+ K+ ATPase.
Targets
| ATPase | ||||
| In vitro | DMSO | 36 mg/mL (173.68 mM) | |
| Water | Insoluble | ||
| Ethanol | 36 mg/mL (173.68 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 48.24 mL | 241.2 mL | 482.39 mL |
| 0.5 mM | 9.65 mL | 48.24 mL | 96.48 mL |
| 1 mM | 4.82 mL | 24.12 mL | 48.24 mL |
| 5 mM | 0.96 mL | 4.82 mL | 9.65 mL |
*The above data is based on the productmolecular weight 207.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10213 |
|---|---|
| CAS No. | 29342-05-0 |
| Formula | C12H17NO2 |
| M. Wt | 207.3 |
| Purity | >98% |
| Synonyms | Batrafen, Loprox, Mycoster, Stieprox, HOE 296b |
| SMILES | CC1=CC(=O)N(C(=C1)C2CCCCC2)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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