Ciclopirox

Catalog No.: A10213

Ciclopirox

Ciclopirox Chemical Structure

CAS NO. 29342-05-0

Ciclopirox is currently being investigated as an alternative treatment to ketoconazole for seborrhoeic dermatitis as it suppresses growth of the yeast Malassezia furfur.It acts by inhibiting the membrane transfer system by interrupting the Na+ K+ ATPase.

Availability: In stock

Package Price Qty
50 mg
$54.00
100 mg
$80.00
10mM * 1mL in DMSO
$50.00
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  • Katsuhisa Morita, .et al. Decomposition profile data analysis of multiple drug effects identifies endoplasmic reticulum stress-inducing ability as an unrecognized factor, Sci Rep, 2020, 10: 13139 PMID: 32753643

Biological Activity

Ciclopirox is currently being investigated as an alternative treatment to ketoconazole for seborrhoeic dermatitis as it suppresses growth of the yeast Malassezia furfur.It acts by inhibiting the membrane transfer system by interrupting the Na+ K+ ATPase.
Targets
ATPase
In vitro DMSO 36 mg/mL (173.68 mM)
Water Insoluble
Ethanol 36 mg/mL (173.68 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 48.24 mL 241.2 mL 482.39 mL
0.5 mM 9.65 mL 48.24 mL 96.48 mL
1 mM 4.82 mL 24.12 mL 48.24 mL
5 mM 0.96 mL 4.82 mL 9.65 mL

*The above data is based on the productmolecular weight 207.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10213
CAS No. 29342-05-0
Formula C12H17NO2
M. Wt 207.3
Purity >98%
Synonyms Batrafen, Loprox, Mycoster, Stieprox, HOE 296b
SMILES CC1=CC(=O)N(C(=C1)C2CCCCC2)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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