CJ-17493 is a neurokinin-1 (NK1) receptor antagonist with a potent Ki of 0.2 nM. This compound also exhibits moderate affinity for the verapamil-binding site of L-type calcium channels (IC50 = 164 nM) and site 2 of sodium channels (IC50 = 48 nM). CJ-17493 is valuable for research applications focused on neurological disorders, providing insights into receptor signaling and potential therapeutic interventions.
CJ-17493 is a neurokinin-1 (NK1) receptor antagonist with a potent Ki of 0.2 nM. This compound also exhibits moderate affinity for the verapamil-binding site of L-type calcium channels (IC50 = 164 nM) and site 2 of sodium channels (IC50 = 48 nM). CJ-17493 is valuable for research applications focused on neurological disorders, providing insights into receptor signaling and potential therapeutic interventions.
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