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Clafen (Cyclophosphamide)

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Catalog No. A10224

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Clafen 100mg A10224-100

Regular Price: $75.00

Special Price: $67.50

Clafen 500mg A10224-500

Regular Price: $250.00

Special Price: $225.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Clafen (Cyclophosphamide) is a nitrogen mustard alkylating agent. An alkylating agent adds an alkyl group (CnH2n+1) to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring.

Clafen (Cyclophosphamide)

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Publications citing Adooq Products
Clafen (Cyclophosphamide) Citations (3)
  • Takashi Azuma,et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
  • Azuma T,et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 28660504
  • Azuma T,et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 26802347

Chemical Information

Catalog Num A10224
Actions N/A
M. Wt 261.1
Formula C7H15Cl2N2O2P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 50-18-0
Synonyms Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane
SMILES code C1CNP(=O)(OC1)N(CCCl)CCCl
Chemical Name (RS)-N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

Biological Activity

Description
Clafen (Cyclophosphamide) is a nitrogen mustard alkylating agent. An alkylating agent adds an alkyl group (CnH2n+1) to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.3 mL 191.5 mL 383mL
0.5 mM 7.66 mL 38.3 mL 76.6 mL
1 mM 3.83 mL 19.15 mL 38.3 mL
5 mM 0.77 mL 3.83 mL 7.66 mL

*The above data is based on the productmolecular weight 261.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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