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- M.D. Valyear,et al. Divergent mesolimbic dopamine circuits support alcohol-seeking triggered by discrete cues and contexts, bioRxiv, 2018, 2018
|Storage||at -20°C 3 years Powder|
|Synonyms||Clozaril, Fazaclo, HF 1854, Iprox, Klozapol, Leponex|
|Clozapine displays a broad range of pharmacological actions; the antipsychotic effects are thought to be mediated principally by 5-HT2A/2C and dopamine receptor blockade.|
|Solubility (25°C)*||In vitro||DMSO||65 mg/mL (198.88 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||32 mg/mL (97.91 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||30.6 mL||153 mL||306mL|
|0.5 mM||6.12 mL||30.6 mL||61.2 mL|
|1 mM||3.06 mL||15.3 mL||30.6 mL|
|5 mM||0.61 mL||3.06 mL||6.12 mL|
*The above data is based on the productmolecular weight 326.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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