Clozapine

Catalog No.: A10236

Clozapine

Clozapine Chemical Structure

CAS NO. 5786-21-0

Clozapine displays a broad range of pharmacological actions; the antipsychotic effects are thought to be mediated principally by 5-HT2A/2C and dopamine receptor blockade.

Availability: In stock

Package Price Qty
500 mg
$50.00
1000 mg
$90.00
2000 mg
$150.00
10mM * 1mL in DMSO
$59.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Yutaro Kobayashi, .et al. Clozapine-dependent inhibition of EGF/neuregulin receptor (ErbB) kinases, Transl Psychiatry, 2019, 9:181 PMID: 31371697
  • M.D. Valyear, .et al. Divergent mesolimbic dopamine circuits support alcohol-seeking triggered by discrete cues and contexts, bioRxiv, 2018, 2018

Biological Activity

Clozapine displays a broad range of pharmacological actions; the antipsychotic effects are thought to be mediated principally by 5-HT2A/2C and dopamine receptor blockade.
Targets
5-HT2
In vitro DMSO 65 mg/mL (198.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol 32 mg/mL (97.91 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.6 mL 153 mL 306 mL
0.5 mM 6.12 mL 30.6 mL 61.2 mL
1 mM 3.06 mL 15.3 mL 30.6 mL
5 mM 0.61 mL 3.06 mL 6.12 mL

*The above data is based on the productmolecular weight 326.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10236
M. Wt 326.8
Formula C18H19ClN4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 5786-21-0
Synonyms Clozaril, Fazaclo, HF 1854, Iprox, Klozapol, Leponex
SMILES CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Clozapine | Clozapine Supplier | purchase | cost | manufacturer | order | distributor | buy 5786-21-0| 5786-21-0 Supplier | purchase 5786-21-0 | 5786-21-0 cost | 5786-21-0 manufacturer | order 5786-21-0 | 5786-21-0 distributor
Rewards