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Publications citing Adooq Products
Clozapine Citations (1)
- M.D. Valyear,et al. Divergent mesolimbic dopamine circuits support alcohol-seeking triggered by discrete cues and contexts, bioRxiv, 2018, 2018
Chemical Information
| Catalog Num | A10236 |
|---|---|
| Actions | N/A |
| M. Wt | 326.8 |
| Formula | C18H19ClN4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 5786-21-0 |
| Synonyms | Clozaril, Fazaclo, HF 1854, Iprox, Klozapol, Leponex |
| SMILES code | CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl |
| Chemical Name | 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine |
Description |
Clozapine displays a broad range of pharmacological actions; the antipsychotic effects are thought to be mediated principally by 5-HT2A/2C and dopamine receptor blockade. | ||||||||||
Targets |
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| Solubility (25°C)* | In vitro | DMSO | 65 mg/mL (198.88 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 32 mg/mL (97.91 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.6 mL | 153 mL | 306mL |
| 0.5 mM | 6.12 mL | 30.6 mL | 61.2 mL |
| 1 mM | 3.06 mL | 15.3 mL | 30.6 mL |
| 5 mM | 0.61 mL | 3.06 mL | 6.12 mL |
*The above data is based on the productmolecular weight 326.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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