Cobimetinib hemifumarate

Catalog No.: A18033

MEK1 inhibitor

Cobimetinib hemifumarate

Cobimetinib hemifumarate Chemical Structure

CAS NO. 1369665-02-0

Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM.

Availability: In stock

Package Price Qty
5 mg
$108.00
10 mg
$186.00
50 mg
$552.00
100 mg
$1,104.00
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Biological Activity

Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.45 mL 77.23 mL 154.47 mL
0.5 mM 3.09 mL 15.45 mL 30.89 mL
1 mM 1.54 mL 7.72 mL 15.45 mL
5 mM 0.31 mL 1.54 mL 3.09 mL

*The above data is based on the productmolecular weight 647.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18033
Actions Inhibitor
M. Wt 647.38
Formula C25H25F3IN3O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1369665-02-0
Synonyms GDC-0973 hemifumarate, GDC0973, GDC 0973; XL-518 hemifumarate, XL518, XL 518
SMILES OC1([[email protected]]2NCCCC2)CN(C1)C(C3=C(C(F)=C(C=C3)F)NC4=C(C=C(C=C4)I)F)=O.O=C(O)/C=C/C(O)=O.[0.5]

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