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Cobimetinib (racemate)

MEK inhibitor

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Catalog No. A15050
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Availability: Out of stock

Product Name Catalog No. Price
Cobimetinib (racemate) 5mg A15050-5
€133.00
Cobimetinib (racemate) 10mg A15050-10
€199.50
Cobimetinib (racemate) 25mg A15050-25
€399.00

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Quick Overview

Cobimetinib is a potent, highly selective inhibitor of MEK1/2.

Cobimetinib (racemate)

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Chemical Information

Catalog Num A15050
Actions Inhibitor
M. Wt 531.31
Formula C21H21F3IN3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 934662-91-6
Synonyms GDC-0973 racemate, XL-518, GDC 0973, XL 518, GDC0973, XL518
SMILES code C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O
Chemical Name [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-(3-hydroxy-3-piperidin-2-ylazetidin-1-yl)methanone

Biological Activity

Description
 Cobimetinib is a potent, highly selective inhibitor of MEK1/2.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.82 mL 94.11 mL 188.21mL
0.5 mM 3.76 mL 18.82 mL 37.64 mL
1 mM 1.88 mL 9.41 mL 18.82 mL
5 mM 0.38 mL 1.88 mL 3.76 mL

*The above data is based on the productmolecular weight 531.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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