COR627 is a positive allosteric modulator of the GABA receptor, designed to enhance GABAergic activity. It increases the affinity for GABA(B) receptors, as demonstrated through its effects on both GABA and baclofen stimulation in rat cortical membranes. In vivo studies indicate that COR627 can amplify the sedative and hypnotic effects of baclofen, even at doses that are otherwise ineffective without pretreatment, making it a valuable tool for research in neuropharmacology and psychotropic drug studies.
COR627 is a positive allosteric modulator of the GABA receptor, designed to enhance GABAergic activity. It increases the affinity for GABA(B) receptors, as demonstrated through its effects on both GABA and baclofen stimulation in rat cortical membranes. In vivo studies indicate that COR627 can amplify the sedative and hypnotic effects of baclofen, even at doses that are otherwise ineffective without pretreatment, making it a valuable tool for research in neuropharmacology and psychotropic drug studies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
