Costunolide

Catalog No.: A10240

Telomerase inhibitor

Costunolide Chemical Structure

CAS NO. 553-21-9

Costunolide is an Inhibitor of human telomerase activity (IC50 = 65 μM in MCF-7 breast cancer cells). It is described to act as an antioxidant, anti-mycobacterial, anti-inflammatory, and anti-viral, with cytotoxic activity.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$90.00
50 mg
$330.00
10mM * 1mL in DMSO
$82.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Costunolide is an Inhibitor of human telomerase activity (IC50 = 65 μM in MCF-7 breast cancer cells). It is described to act as an antioxidant, anti-mycobacterial, anti-inflammatory, and anti-viral, with cytotoxic activity.
Targets
FPTase Telomerase (MDA-MB-231) Telomerase (MCF-7)
20 μM65 μM90 μM
In vitro DMSO 47 mg/mL (202.3 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL (4.3 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 43.05 mL 215.24 mL 430.48 mL
0.5 mM 8.61 mL 43.05 mL 86.1 mL
1 mM 4.3 mL 21.52 mL 43.05 mL
5 mM 0.86 mL 4.3 mL 8.61 mL

*The above data is based on the productmolecular weight 232.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10240
Actions Inhibitor
M. Wt 232.3
Formula C15H20O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 553-21-9
Synonyms N/A
SMILES CC1=CCC/C(=C/[[email protected]@H]2[[email protected]@H](CC1)C(=C)C(=O)O2)/C

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