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  1. Telomerase Inhibitor

    BIBR 1532 is a selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively).

  2. Telomerase inhibitor

    Costunolide is an Inhibitor of human telomerase activity (IC50 = 65 μM in MCF-7 breast cancer cells). It is described to act as an antioxidant, anti-mycobacterial, anti-inflammatory, and anti-viral, with cytotoxic activity.
  3. Amsacrine (m-AMSA) is an anticancer agent that displays activity against refractory acute leukemias as well as Hodgkin's and non-Hodgkin's lymphomas.
  4. topoisomerase 1 inhibitor

    Genz-644282 is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity.
  5. Telomerase substrate

    6-thio-dG is a nucleoside analog and telomerase substrate.
  6. Telomerase inhibitor

    RHPS4 is a potent inhibitor of Telomerase at submicromolar.
  7. telomerase inhibitor

    TMPyP4 tosylate (TMP 1363) is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.
  8. telomerase activation agent

    Astramembrangenin (Cycloastragenol) is a compound isolated from the roots of Astragalus kuhitangi (Nevski) Sirj.

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